Sustainability science is the field that is focused on examining the interactions between human, environmental, and engineered systems to understand and contribute to solutions. Indoor environmental quality (IEQ) refers to the quality of a building’s environment in relation to the health and wellbeing of those who occupy space within it. In the course, we focus on the relation among sustainability science, IEQ and health. The design of IEQ for health improvement will discuss in the course. Aging is one of the biggest issues in the developed countries. The course reviews the relationship between indoor environment and health conditions mainly for elderly people to find the problems, and we discuss how to improve the indoor environment from the point of view of healthy life.